Some Health Hazards of Manganese Exposure Among Egyptian Workers
Khadiga Salah Ibrahim1, Mohamed Samir El-Attar2, Hossam El-Din El-Anwar
Amin2, Anan Moustafa El-Mishad1, and Heba Mahdy Abd-Alla1
1 Department of Industrial Medicine and Occupational Health, National Research Center, Cairo, Egypt
2 Department of Industrial Medicine and Occupational Health,. Cairo University, Cairo, Egypt
Corresponding author: Dr. Khadiga Salah Ibrahim
Mailing address: Department of Industrial Medicine and Occupational
Health National Research Center
Dokki, Cairo, Egypt.
Fax number: 2023370931 - 2023601877
E-mail adress: khadigasalah@yahoo.com
CEJOEM 2001, Vol.7. Nos.3-4.:228-236
Key words:
Manganese, occupational exposure, health hazards, pulmonary function, immunoglobulins
Abbreviations:
FEV1 = Forced Expiratory Volume in one second
FVC = Forced Vital Capacity
VC = Vital Capacity
Abstract:
Health hazards to maganese exposure were examined in 69 male workers employed in iron and
steel industry (mean duration of exposure 18.42 ± 6.6 yr) and in 31 healthy workers as a control
group. Both groups underwent full clinical examination. Blood analysis comprising haemoglobin (Hb)
concentration, red and white blood cell counts, differential leukocyte cell count, determination of
Mn concentration in blood, determination of IgG, IgM, and pulmonary ventilatory function tests were
performed.
In the exposed group, blood cell counts and Hb levels showed
statistically significant reduction as compared to the control group, while serum
immunoglobulin levels showed statistically significant elevation. There was no correlation
between the blood Mn concentration and any of the parameters mentioned above. The values of
the pulmonary ventilatory function tests (FEV1, FVC/VC%, FEV1/FVC%) were significantly reduced
in the exposed workers.
Received: 17 September 2001
Accepted: 6 December 2001
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