CEJOEM 1996; 2(4):329–334
Abstract: The study of micronuclei was performed on
human hepatoma cells (Hep G2) treated in vitro with polluted water samples
taken from waste water from some selected industrial processing plants
in Kraków: 1. the coke-oven division and the steel foundry in the
steel mill, 2. the thermal-electric power station, 3. the institute of
machining, 4. the pharmaceutical factory, 5. the car-engine repair plant,
6. the waste water purification station. The frequencies of mic-ro-nuclei
(MN) increased significantly in the cells treated with the polluted water
samples (1–6.6 %). The results were higher than in control (0.8–1.1 %).
The highest number of MN was found in the cells treated with water from
the coke-oven. The results indicate that micronucleus assay is a sensitive
test for the measurements of potential genotoxicity of water pollutants.
Key words: Micronuclei, water pollutants, industrial plants, HepG2 cells
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