Cytogenetic Monitoring of Radiological and Nuclear Worker
Doina C. Obreja1, Gabriella Bognár2, Katalin Szalma2, and György J. Köteles2
1 Institute of Public Health, Bucharest, Romania
2 “Frédéric Joliot-Curie” National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary
Corresponding author: Dr. Gabriella Bognár
“Frédéric Joliot-Curie” National Research Institute for Radiobiology and Radiohygiene
POB. 101
H-1775 Budapest, Hungary
Telephone: +36-1-482-2000/121
E-mail: bognar@hp.osski.hu
CEJOEM 2007, Vol.13. No.1.: 17–24
Key words:
Lymphocyte, micronuclei, translocations, monitoring, radiological and nuclear workers
Abstract:
Micronucleus analysis and translocation detection by fluorescent in situ hybridization (FISH) technique
in lymphocytes of radiological and nuclear workers were performed. None of the persons involved were exposed to
over the occupational annual dose limits. Micronucleus frequencies tended to increase in function of cumulative
exposure expressed by working years, though not overwhelming 40 per thousand cells, i.e. slightly more than the
range of the occupationally not exposed population category. The translocation detection by FISH has not lead
to detectable result for the persons cumulating 100–250 mSv during their working years.
Received: 15 February 2007
Accepted: 28 May 2007
| Back |